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What is Microdosing?

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DISCLAIMER/Harm Reduction: Microdosing as it pertains to psychedelics is not yet legal in most jurisdictions. This site and its contents are for informational purposes only and are focused on the potential future of legal, licensed clinical therapy, and in no way is intended to recommend or direct towards current use or obtaining illicit substances. Please read our full disclaimer.

It is important to understand that using any psychedelic products from the street has significant risks, and is unlikely to produce the promising results emerging in some clinical trials which involve particular dosing and purity, along with specific, carefully crafted psychotherapy in a safe, controlled environment. Various psychedelics purchased illegally often are adulterated with other, possibly harmful substances, making it difficult to dose properly for PTSD, anxiety, or depression treatment or any kind of therapeutic purpose.

At this current time, until medical-use is legalized, anyone interested in microdosing-assisted therapy should focus solely on educating themselves through credible publications and scientific journals, and may inquire about potential legal clinical trials.

Always consult with a licensed physician before beginning any therapy protocol, and be sure to know your jurisdiction's laws and regulations concerning such protocols.

A potential future in which microdosing psychedelics under the care of licensed, clinical therapists is evolving, as hundreds of millions of dollars are being poured into clinical trials, by companies backed by top institutional investors, working with renowned universities around the globe

While more research is needed, previous studies indicate that some of the conditions that may be treated with microdosing include:

  • Post Traumatic Stress Disorder (PTSD)
  • Anxiety
  • Depression
  • Alcohol Addiction
Adults who microdose psychedelics report health related motivations and lower levels of anxiety and depression compared to non-microdosers


What is Microdosing?

In general, a microdose is considered to be one tenth of a dose normally causing hallucinogenic effects. Generally, this involves a frequency that ranges between 2 and 4 times a week, and a duration of a few weeks, to months, or even years, although the latter is rare.

What Are the Potential Benefits?

Reported short-term benefits of microdosing include an increase in positive mood, a decrease in negative mood, and in improvement relationships with others and their environment, which seems to be in line with the effects of full psychedelic doses, though without the perceptual effects.

What Are the Potential Risks?

Acute negative effects may occur when individuals are under the influence of psychedelics including psychological (‘increased anxiety’) or physiological (‘discomfort’) changes.

Some suggest that this increased anxiety is linked to the surface emergence of latent emotional content as a result of the microdosing. Along the same lines, it is reasoned that this could accelerate a healing process in a therapeutic context because these emotions can then be explored.

To date, there has not been comprehensive enough studies to rule out other potential risks or dangers. There are currently approximately 100 clinical trials recruiting for the study of psychedelic-assisted therapies.

Is a Microdose Safe?

While it is critical to always consult a licensed healthcare professional; with regard to safety, studies have demonstrated that low doses are well tolerated (in healthy volunteers) and have no-to-minimal effects on physiological measures. -

How Might it Help with Depression Treatment?

While further research is needed and is currently underway as to whether psychedelic microdosing is of therapeutic value for depression, the effects on selective processes suggest that low doses of psychedelics could play a role in treating depression by inducing cognitive flexibility, which may lead to decreased rumination.

Future placebo-controlled clinical trials in depressed patients are required to understand the therapeutic value of microdosing psychedelics, how this may differ from therapy using standard psychedelic dosing, and whether different substances have different effect patterns.

This proposed research will give new insights into the potential of future alternative psychiatric treatment forms that are urgently needed, given the often suboptimal results of current treatments.

Microdosing In the News

The Hollywood Reporter The Hollywood Reporter
Inside the Growing Wellness Trend of Psilocybin Mushroom Microdosing
Amid a push to legalize so-called "magic mushrooms" in California, research accelerates into their health benefits ...
Thrillist Thrillist
Best 2022 Wellness Trend? Tripping at a Psychedelic Retreat
I fast became a believer. Plant medicine, when used correctly, is a powerful tool in my mental health arsenal.
Screen Rant Screen Rant
RHOC: Why Fans Are Enjoying Watching The Housewives ‘Microdosing’ Edibles
Heather gifts Shannon some edible gummies and explains how she takes tiny "microdoses." Fans enjoy seeing the ...
Insider Insider
Moms who microdose 'magic' mushrooms say the psychedelic made them better parents
Three moms told Insider that taking small amounts of psilocybin, the ingredient in "magic" mushrooms, helped ...
AdAge AdAge
Why creatives should microdose lsd and cannabis before big pitches
Microdosing is the future of wellness, according to futurist Faith Popcorn and Canopy's Julian Cohen at Advertising ...
Cosmopolitan Cosmopolitan
Meet the women who regularly microdose psychedelics
Is 'magic mushroom therapy' really the key to better mental health?
Huffpost Huffpost
I'm A Mom Microdosing Magic Mushrooms. Here's How It's Changing How I See The World
"It’s not the ’60s and I’m not a hippie. Neither am I in my experimental teens or 20s. Yet here I am: a mom on ...
Forbes Forbes
Silicon Valley Is Micro-Dosing ‘Magic Mushrooms’ To Boost Their Careers
Silicon Valley, the home of Facebook, Apple, Google and Twitter, is the embodiment of the hustle culture.
Independent Independent
'Microdosing' LSD is not just a Silicon Valley trend – it is spreading to other workplaces
It started off as an underground practice in Silicon Valley, tried by Steve Jobs and Bill Gates
GQ Magazine GQ Magazine
Silicon Valley's extreme new productivity hack: LSD
Who are the tech execs illegally 'microdosing' one of the most powerful psychoactive substances in the world? Hayden Vernon went on the hunt
Psychcentral Psychcentral
Microdosing Psychedelics Linked to Lower Anxiety, Depression, Stress
Psychedelic microdosing has increased as a coping tool for mental health concerns during the COVID-19 pandemic ...